Multiple Myeloma and Dentistry
نویسندگان
چکیده
Multiple myeloma (MM) is a malignant neoplasm of plasma cells that is characterized by the production of pathologic M proteins, bone lesions, kidney disease, hyperviscosity, and hypercalcemia. MM occurs more frequently in patients between 50 and 80 years of age, with a mean age of 60 years and man are more affected than women (1). Systemic symptoms are due to bone pain pathologic fractures, renal failure, hypercalcemia, weight loss, fatigue, weakness, fever, thrombocytopenia, neutropenia, diarrhea, orthostatic hypotension and infections (2, 3). Initial findings are bone pain in 68% of patients, anemia in 62%, renal insufficiency in 55%, hypercalcemia in 30%, hepatomegaly in 21%, and splenomegaly in 5%. (4)
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